Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea
ABSTRACT
Fascioliasis is a zoonotic infection by Fasciloa hepatica, a liver fluke that infests cattle and sheep. Humans are infected by eating water plants contaminated with metacercariae. Fasciola hepatica causes liver abscess, cholangitis, common bile duct obstruction and so on. We report a 42-year-old woman who presented with epigastric pain radiating to back and eosinophilia. During follow-up period, liver function was worsen transiently and abdominal computed tomography showed hypodense area in caudate lobe. She was diagnosed with sphincter of Oddi dysfunction on manometry. Endoscopic sphincterotomy was conducted, but epigastric pain was not changed. Additionally we diagnosed fascioliasis serologically. Triclabendazole, treatment of cholice for fascioliasis, cannot be got all over the world. We have tried albendazole and praziquantel, but clinical improvement was not observed. Recently nitazoxanide was given to her, and we are observing clinical course. This report suggests that sphincter of Oddi dysfunction can be caused by fascioliasis.
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