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Korean J Pancreas Biliary Tract > Volume 17(1):2012 > Article
The Korean Journal of Pancreas and Biliary Tract 2012;17(1):44-46.
간문부 담관암과 유사한 소견을 보인 면역글로불린 G4 연관 경화성 담관염
장지웅, 김명환1, 김태균1, 박도현1, 이상수1, 서동완1, 이성구1
을지대학교 의과대학 을지대학교병원 소화기내과, 1울산대학교 의과대학 서울아산병원 소화기내과"
Immunoglobulin G4-associated Sclerosing Cholangitis Mimicking Hilar Cholangiocarcinoma
Ji Woong Jang, Myung-Hwan Kim1, Tae Gyoon Kim1, Do Hyun Park1, Sang Soo Lee1, Dong-Wan Seo1, Sung-Koo Lee1
Department of Gastroenterology, Eulji University College of Medicine, Eulji University Hospital, Daejeon, 1Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
ABSTRACT
Immunoglobulin G4 (IgG4)-associated sclerosing cholangitis is a steroid responsive biliary disease, frequently involving the bile duct, that is often associated with autoimmune pancreatitis. It is characterized by elevation of immunoglobulin G4 in serum and infiltration of immunoglobulin G4 positive plasma cells in bile ducts. The clinically important thing is to differentiate this rare disease from primary sclerosing cholangitis and cholangiocarcinoma. However, the preoperative diagnosis is likely to be missed due to the lack of specific symptoms and specific imaging features. Therefore, making an early diagnosis requires a high index of suspicion. This article reports on a 71-year-old man with IgG4-associated sclerosing cholangitis mimicking hilar cholangiocarcinoma.
Keywords: Immunoglobulin G4, Sclerosing cholangitis, Cholangiocarcinoma, Autoimmune pancreatitis
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