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Korean J Pancreas Biliary Tract > Volume 18(2):2013 > Article
The Korean Journal of Pancreas and Biliary Tract 2013;18(2):53-57.
급성 백혈병의 전구 증상으로 반복적인 담도 담석의 발생이 가능한가?
김기배, 한정호, 이주영, 김은비, 이동화, 박순영, 김의중, 박선미
충북대학교 의과대학 내과학교실
Can Recurrent Bile Duct Stones Presage Leukemia?
Ki Bae Kim, Joung-Ho Han, Jooyoung Lee, Eun Bee Kim, Dong-Hwa Lee, Soon-Young Park, Eui Joong Kim, Seon Mee Park
Department of Internal medicine, Chungbuk National University College of Medicine, Cheongju-si, Republic of Korea
ABSTRACT
A 48-year-old woman visited the emergency room for abdominal pain and fever. She had undergone large common bile duct (CBD) stone extraction with endoscopic retrograde cholangiopancreatography (ERCP) ten times in the previous 14 months. We initially thought that the rapid, recurrent bile duct stone production was due to the dilatation of the CBD diameter, so we had planned a hepaticojejunostomy. However, the serum white blood cell count at 11th visit was 113,500/μ, and computed tomography showed multiple CBD stones. To resolve the cholangitis, ERCP with lithotripsy was performed. A peripheral blood smear and bone marrow biopsy revealed acute myeloid leukemia, and induction chemotherapy was started. Risk factors for recurrent CBD stones include biliary stasis due to anatomical problems, systemic disease such as hemolytic anemia, and altered immune mechanism and bacterial overgrowth. We report a patient in whom bile duct stones recurred over several months before the onset of acute leukemia.
Keywords: acute myeloid leukemia, obstructive jaundice, bile ducts, endoscopic retrograde cholagiopancreatography
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Clinical Progress of the Bile Duct Stones   1999 September;4(2)
Recurrent Common Bile Duct Stone  2008 September;13(2)
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