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Korean J Pancreas Biliary Tract > Volume 18(2):2013 > Article
The Korean Journal of Pancreas and Biliary Tract 2013;18(2):62-66. doi: https://doi.org/10.15279/kpba.2013.18.2.62
다발성 간전이를 동반한 췌장신경내분비종양 환자의 장기생존 1예
장동기, 박진명, 이민종, 최지민, 최영훈, 한유민, 유정주, 류지곤
서울대학교 의과대학 내과학교실, 간연구소"
A Case of Long-term Survivor of Pancreatic Neuroendocrine Tumor with Multiple Liver Metastases
Dong Kee Jang, Jin Myung Park, Minjong Lee, Ji Min Choi, Young Hoon Choi, Yoo Min Han, Jeong-Ju Yoo, Ji Kon Ryu
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine
A 50-year-old female with epigastric pain was diagnosed as pancreatic neuroendocrine tumor with multiple liver metastases by radiologic imaging studies and liver biopsy. After 4 times of transarterial chemoembolizations (TACE), pylorus-preserving pancreaticoduodenectomy (PPPD) was performed and Grade 2 pancreatic neuroendocrine tumor was confirmed. Although new liver metastases were detected after the surgery, no further treatment has been given due to very slow growth of the metastatic lesions. The patient has survived for over 7 years with no symptoms related to cancer. This case suggests that a patient with pancreatic neuroendocrine tumor with multiple liver metastases could become a long-term survivor by aggressive locoregional treatments including surgery. Therefore, active multidisciplinary approaches should be considered for advanced pancreatic neuroendocrine tumors.
Keywords: gastro-enteropancreatic neuroendocrine tumor, neoplasm metastasis, liver
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