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Korean J Pancreas Biliary Tract > Volume 18(3):2013 > Article
The Korean Journal of Pancreas and Biliary Tract 2013;18(3):28-31. doi: https://doi.org/10.15279/kpba.2013.18.3.28
특발성 성인성 담관감소증 1예
강진구1, 장명국1, 이지운1, 김은정1, 김미희1, 양보경1, 조성진2
특발성 성인성 담관감소증 1
A Case of Idiopathic Adulthood Ductopenia
Jin Gu Kang1, Myoung Kuk Jang1, Ji Un Lee1, Eun Jung Kim1, Mi Hee Kim1, Bo Kyung Yang1, Sung Jin Cho2
Department of Internal Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, 2Department of Pathology, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea,
Idiopathic adulthood ductopenia (IAD) is a rare adult onset chronic cholestatic disease of unknown etiology without the existence of inflammatory bowel disease. IAD has characteristics of autoantibody absence in lab findings and loss of interlobular bile ducts in biopsy. A 28-year-old man admitted to the hospital with an incidental finding of elevated transaminases and alkaline phosphatase on routine health screening. The viral hepatitis markers and autoimmune hepatitis antibodies were all negative. The patient showed a radiologically normal anatomy of extrahepatic biliary tree. Histological examination of four liver biopsy specimens showed severe ductopenia on all portal tracts. We, herein, report a rare case of IAD with a brief review of literature.
Keywords: idiopathic adulthood ductopenia, cholestasis
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